Cell- and tissue damage
Knocking out LOX-1 limits myocardial ischemia-reperfusion injury in mice.
Lectin-like oxidized low-density lipoprotein receptors (e.g LOX-1) are upregulated during myocardial ischemia-reperfusion, and appear to be associated with apoptosis, necrosis, and left ventricular functional deterioration. (Cat.# HM2138)
