Hycult Biotech news
Promotion of CpG-DNAs, TLRs, CD14 and IL-1R kits, antibodies and proteins
CD14, known to function as a receptor for LPS, is expressed mainly on the surface of monocytes/macrophages, and polymorphonuclear cells, the cells responsible for scavenging of LPS and bacteria.
The IL-1 system includes two agonists (IL-1 alpha and IL-1 beta), converting enzymes, antagonists, two receptors (IL-1RI and IL-1RII) and the IL-1 receptor accessory protein. Interleukin-1 signal is transduced through the type I receptor.
In mammals, TLR identified as type I transmembrane signaling receptors with pattern recognition capabilities, have been implicated in the innate host defense to pathogens. Examples of ligands that are recognized by the TLRs are LPS, CpG-DNAs and dsRNA.
Valid from the 1st of January 2010 until the 31st of March 2010.
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